Deb was born in St Louis, Missouri. Her father was a Teamster truck driver and her mother a cashier at the local grocery store. She graduated from Affton High School, then attended college at the University of Missouri–Columbia, graduating with a Bachelor of Arts in Political Science in 1989. Immediately upon graduation she was commissioned as an officer in the United States Air Force, and was recognized as the Distinguished Graduate of her ROTC class. In 2004 she earned a Master’s in Management from Webster University.

During her 20-year Air Force career, Deb served in a variety of assignments as a Logistics Plans Officer and an Information Manager. She lived all over the United States and in Iceland, and traveled around the world planning and conducting Air Force operations. Her favorite assignments include serving as the section commander of a Security Forces squadron and collaborating with the U.S. Army to speed delivery of personnel and equipment to combat zones and disaster areas. Throughout her military career, Deb was known for her decisive leadership and her ability to plan and execute complex projects.

After retiring from the Air Force at the rank of major, Deb and her family moved to Lexington Park, Maryland, where she quickly got involved in the local political scene. She was elected President of the Republican Women of St Mary’s in 2010 and president of the Republican Club of St Mary's in 2012. She also took on the roles of Protocol Chair and

Southern Region Chair for the Maryland Federation of Republican Women, and was appointed to be a delegate to the 2012 Republican National Convention in Tampa Bay. Her hard work led to her being named the St Mary's County Republican Woman of the Year for 2013.

Not one to stand still, Deb served as county coordinator for Jim Rutledge’s campaign for U.S. Senate, treasurer for Cindy Jones’ campaign for St Mary's County Commissioner, and communications director for Delegate Tony O'Donnell's bid for U.S. Congress. She also collected signatures to force public referendums on in-state tuition for illegal immigrants and same-sex marriage. In 2014, she successfully ran for the the Maryland House of Delegates, and proudly represents District 29B.

Deb is happily married. She and her husband, Jeff Lathrop, have two children who both attend St Mary's County public schools. She was a Girl Scout troop leader and has participated in the Susan G. Komen 3-day Walk for a Cure for breast cancer and the American Cancer Society's Relay for Life. She enjoys sailing, target shooting and traveling.